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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1830482Generated: October 30, 2026

3,4-Difluorophenylacetylene → 2-Propyl-7-(3,4-difluorophenylethynyl)phenanthrene

https://huagongshe.com/reaction/1830482

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DifluorophenylacetyleneHCID 13878454—
Reactant2-Iodo-7-propyl-phenanthreneHCID 22044694—
CatalystHCID 178418397HCID 178418397—
SolventDimethylformamideHCID 6228—
SolventTriethylamineHCID 8471—
Product2-Propyl-7-(3,4-difluorophenylethynyl)phenanthreneHCID 22045090—

Reaction Steps

2-iodo-7-propyl-phenanthrene in dimethylformamide and triethylamine was reacted with 4-ethynyl-1,2-difluorobenzene in the presence of tetrakis(triphenylphosphine)palladium (0), and the product was purified by silica gel column chromatography (hexane) and then recrystallized from ethanol to yield 2-propyl-7-(3,4-difluorophenylethynyl)phenanthrene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067179B1
Source datasetuspto-grants-2006_06
ORD IDord-ac944e5887e14e1e8f8962fe1013c3f8
Source noteuspto-grants-2006_06