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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 18306Generated: October 26, 2026

1,3-dimethyl-1H-indole-2-carbaldehyde → [(4-fluoro-1H-indol-3-yl)methyl](methyl)amine

https://huagongshe.com/reaction/18306

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-dimethyl-1H-indole-2-carbaldehydeHCID 2771468—
Reactant4-Fluoro-1H-indole-3-carbaldehydeHCID 22139006—
ReactantMethyl 2-((5-bromopyridin-2-yl)amino)acetateHCID 22139049—
Product[(4-fluoro-1H-indol-3-yl)methyl](methyl)amineHCID 22139121—

Reaction Steps

According to the procedure of Preparation 13 (c), except substituting 4-fluoro-1H-indole-3-carboxaldehyde for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound was prepared as a viscous oil: MS (ES) m/e 179 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07741339B2
Source datasetuspto-grants-2010_06
ORD IDord-d3fa868731a74581be3264abcefe2e9d
Source noteuspto-grants-2010_06