Pyrrolidine → HCID 712855, compound

HRID 1830880Notes

Reaction equation

HRID 1830880 reaction equation
[I:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[CH3:11])[C:5](Cl)=[O:6].[NH:12]1[CH2:16][CH2:15][CH2:14][CH2:13]1>>[I:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[CH3:11])[C:5]([N:12]1[CH2:16][CH2:15][CH2:14][CH2:13]1)=[O:6]

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 177521573-Iodo-4-methylbenzoyl chloride

Product 1

HCID 712855HCID 712855, compound

Procedure

By the reaction in the same manner as in Example 26-i) using 3-iodo-4-methylbenzoyl chloride (2.00 g) and pyrrolidine (3.5 ml), the title compound (1.62 g) was obtained as a pale-yellow oil.

Workup

  1. customBy the reaction in the same manner as in Example 26-i)

Sources & evidence

ORD record
ord-376889e92ced4c4492b5b9025936aa43
Source dataset
uspto-grants-2006_06
Patent number
US07067537B2

Reaction notes

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