Hydroxide → N-Cyclopropylmethyl-N-[7-(2,4-dimethoxy-6-methylphenyl)-2-ethylpyrazolo[1,5-a]pyridin-3-yl]-N-tetrahydro-3-furanylmethylamine

HRID 183107Notes

Reaction equation

HRID 183107 reaction equation
[Ba+2:48].[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[n:7]1[n:8][c:9]([CH2:22][CH3:23])[c:10]2[N:11]([CH2:12][CH:13]1[CH2:14][O:15][CH2:16][CH2:17]1)[CH2:18][CH:19]1[CH2:20][CH2:21]1.[CH3:24][O:25][c:26]1[c:27]([O:35][B:36]([OH:37])[OH:38])[c:28]([CH3:34])[cH:29][c:30]([O:32][CH3:33])[cH:31]1.[CH3:50][CH2:51][O:52][C:53](=[O:54])[CH3:55].[CH3:56][O:57][CH2:58][CH2:59][O:60][CH3:61].[OH-:47].[OH-:49].[OH2:39].[OH2:40].[OH2:41].[OH2:42].[OH2:43].[OH2:44].[OH2:45].[OH2:46].[OH2:62].[cH:63]1[cH:64][cH:65][c:66]([P:67]([Pd:68]([P:69]([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)([c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)([P:88]([c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)([c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)[c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[P:107]([c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)([c:114]2[cH:115][cH:116][cH:117][cH:118][cH:119]2)[c:120]2[cH:121][cH:122][cH:123][cH:124][cH:125]2)([c:126]2[cH:127][cH:128][cH:129][cH:130][cH:131]2)[c:132]2[cH:133][cH:134][cH:135][cH:136][cH:137]2)[cH:138][cH:139]1>>[c:2]1(-[c:27]2[c:26]([O:25][CH3:24])[cH:31][c:30]([O:32][CH3:33])[cH:29][c:28]2[CH3:34])[cH:3][cH:4][cH:5][c:6]2[n:7]1[n:8][c:9]([CH2:22][CH3:23])[c:10]2[N:11]([CH2:12][CH:13]1[CH2:14][O:15][CH2:16][CH2:17]1)[CH2:18][CH:19]1[CH2:20][CH2:21]1

Participants

9

Reactant 8

HCID 961Hydroxide2×HCID 962Water9×HCID 80711,2-DimethoxyethaneHCID 8857Ethyl AcetateHCID 104810Barium ionHCID 21984575N-(7-bromo-2-ethylpyrazolo[1,5-a]pyridin-3-yl)-N-cyclopropylmethyl-N-tetrahydro-3-furanylmethylamineHCID 219847402,4-Dimethoxy-6-methylphenylboric acidHCID 178420554HCID 178420554, compound

Product 1

HCID 21984551N-Cyclopropylmethyl-N-[7-(2,4-dimethoxy-6-methylphenyl)-2-ethylpyrazolo[1,5-a]pyridin-3-yl]-N-tetrahydro-3-furanylmethylamine

Sources & evidence

ORD record
ord-6091953fd5f541089b4b571a6387a7f7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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