4-Benzylphenol → Methyl-phenyl-carbamic Acid 4-benzyl-phenyl Ester

HRID 1831095Notes

Reaction equation

HRID 1831095 reaction equation
[CH2:1]([C:8]1[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:15][N:16]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[C:17](Cl)=[O:18]>>[CH2:1]([C:8]1[CH:9]=[CH:10][C:11]([O:14][C:17](=[O:18])[N:16]([CH3:15])[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[CH:12][CH:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 75634-BenzylphenolHCID 77969Carbamic chloride, N-methyl-N-phenyl-

Product 1

HCID 10125687Methyl-phenyl-carbamic Acid 4-benzyl-phenyl Ester

Procedure

The title compound was prepared from 4-benzyl-phenol and N-methyl-N-phenylcarbamoyl chloride. The crude product was recrystallized (ethanol/water) (56%, white crystals). HPLC-MS m/z=318.1 (M+l), Rt: 5.05 min.

Workup

  1. customThe crude product was recrystallized (ethanol/water) (56%, white crystals)

Sources & evidence

ORD record
ord-1c5a8fc24c6f4c39a0354f3ff888fcde
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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