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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1831337생성일: 2026년 10월 27일

Potassium Bromide → 4-(Pyrazin-2-yl)-piperazine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl Ester

https://huagongshe.com/reaction/1831337

반응식

참여 물질

역할이름HCID투입량
반응물Potassium BromideHCID 253877—
반응물1-PiperazinylpyrazineHCID 2734639—
반응물4-(5-Trifluoromethylpyridin-2-yloxy)-phenyl chloroformateHCID 22047762—
생성물4-(Pyrazin-2-yl)-piperazine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl EsterHCID 69519388—

반응 단계

The title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl chloroformate and 1-(pyrazin-2-yl)-piperazine- White crystals, m.p. 160–161° C.; HPLC-MS: m/z=446 (M+1) at Rt=4.0 min.; 1H NMR (DMSO-d6): δ 8.60–8.57 (m, 1H), 8.39–8.36 (m, 1H), 8.27–8.22 (dd-like, 1H), 8.14–8.11 (m, 1H)7.91–7.87 (d-like, 1H), 7.29–7.21 (m, 5H), 3.80–3.64 (br, 6H), 3.64–3.50 (br, 2H); IR (KBr): ν 1737, 1714 (C═O) cm−1.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07067517B2
출처 데이터셋uspto-grants-2006_06
ORD IDord-2358c731a61a4a218b3c1d47f878c69e
출처 메모uspto-grants-2006_06