反应详情

The title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl chloroformate and 1-(pyrazin-2-yl)-piperazine- White crystals, m.p. 160–161° C.; HPLC-MS: m/z=446 (M+1) at Rt=4.0 min.; 1H NMR (DMSO-d6): δ 8.60–8.57 (m, 1H), 8.39–8.36 (m, 1H), 8.27–8.22 (dd-like, 1H), 8.14–8.11 (m, 1H)7.91–7.87 (d-like, 1H), 7.29–7.21 (m, 5H), 3.80–3.64 (br, 6H), 3.64–3.50 (br, 2H); IR (KBr): ν 1737, 1714 (C═O) cm−1.