Sodium Dithionite → HCID 62705479, compound

HRID 1831500Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][N:12]=[C:11]([NH:15][CH:16]([CH3:20])[CH:17]([CH3:19])[CH3:18])[C:10]=1[N+:21]([O-])=O.[O-]S(S([O-])=O)=O.[Na+].[Na+]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][N:12]=[C:11]([NH:15][CH:16]([CH3:20])[CH:17]([CH3:18])[CH3:19])[C:10]=1[NH2:21]

Participants

Reactant 2

HCID 24489Sodium Dithionite

HCID 22052121HCID 22052121, compound

Product 1

HCID 62705479HCID 62705479, compoundYield 75%

Procedure

[4-(2,4-Dichloro-phenyl)-3-nitro-pyridin-2-yl]-(1,2-dimethyl-propyl)-amine (0.26 g, 0.74 mmol) and Na2S2O4 (1.03 g, 5.94 mmol) were treated substantially as described in Part E of Example 9 to yield 0.18 g (75%) of crude 4-(2,4-dichloro-phenyl)-N2-(1,2-dimethyl-propyl)-pyridine-2,3-diamine: MS (AP) m/z 324.3 [(M+H)+, 70].

Sources & evidence

ORD record: ord-d50332c77f5b4fa9a4a7b351c301e19f
Source dataset: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07067658B2

Reaction notes

Loading…