Lawesson's reagent → HCID 22052533, compound

Participants

Reaction Steps

A solution of 100 mg (0.21 mmol) of 7-(N-tert-butoxycarbonyl-3-chlorobenzyl-amino)-1,2,3,3a,7,8,9,10b-octahydro-dicyclopenta[c,g]quinolin-4-one and 96 mg (0.23 mmol) of Lawesson's reagent in 10 ml of DME is stirred for 2 hours at room temperature. After concentration by evaporation, the residue is purified by column chromatography on silica gel with hexane-ethyl acetate: 70 mg of product.

Provenance & Evidence