Hydrochloric Acid → 4'-Aminomethyl-biphenyl-2-sulfonic Acid Amide Hydrochloride

HRID 1831771Notes

Reaction equation

HRID 1831771 reaction equation
CN(C=[N:5][S:6]([C:9]1[C:10]([C:15]2[CH:20]=[CH:19][C:18]([CH2:21][NH2:22])=[CH:17][CH:16]=2)=[CH:11][CH:12]=[CH:13][CH:14]=1)(=[O:8])=[O:7])C.[ClH:23]>CO>[ClH:23].[NH2:22][CH2:21][C:18]1[CH:19]=[CH:20][C:15]([C:10]2[C:9]([S:6]([NH2:5])(=[O:7])=[O:8])=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:16][CH:17]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 696522884'-Aminomethyl-biphenyl-2-sulfonic Acid Dimethylaminomethyleneamide

Product 1

HCID 696522904'-Aminomethyl-biphenyl-2-sulfonic Acid Amide Hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

400 mg of 4′-Aminomethyl-biphenyl-2-sulfonic acid dimethylaminomethyleneamide were treated with 10 ml MeOH and 4 ml conc. HCl and refluxed for 1 h. Solvent and HCl were evaporated and the product used without purification.

Workup

  1. temperaturerefluxed for 1 h
  2. customSolvent and HCl were evaporated
  3. customthe product used without purification

Sources & evidence

ORD record
ord-b79570ccedc343a9b5489e79a5a70019
Source dataset
uspto-grants-2006_06
Patent number
US07067665B2

Reaction notes

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