HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Hydroxy-4-iodobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Iodine | HCID 807 | — |
| Reactant | 3-Hydroxybenzoic Acid | HCID 7420 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Hydroxy-4-iodobenzoic acid | HCID 736854 | — |
Reaction Steps
To a solution of 26 g 3-Hydroxybenzoic acid and 43 g Na2CO3 in 45 mg H2O at 100° C. was added dropwise a solution of 48 g KI and 48 g iodine in 135 ml H2O. After heating for additional 3 h the mixture was cooled to RT and acidified with concentrated HCl. The title compound precipitated as a white solid and was collected by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07067665B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-784c072c80b041afaac8f5c624fa5185 |
| Source note | uspto-grants-2006_06 |