Allylamine → HCID 54687827, compound

HRID 1832035Notes

Reaction equation

HRID 1832035 reaction equation
[OH:1][C:2]1[CH:7]=[C:6]([CH3:8])O[C:4](=[O:9])[CH:3]=1.[CH2:10]([NH2:13])[CH:11]=[CH2:12]>O>[CH2:10]([N:13]1[C:6]([CH3:8])=[CH:7][C:2]([OH:1])=[CH:3][C:4]1=[O:9])[CH:11]=[CH2:12]

Participants

4

Reactant 2

HCID 7853AllylamineHCID 546757574-Hydroxy-6-methyl-2-pyrone

Product 1

HCID 54687827HCID 54687827, compoundYield 69%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
100 °C

Procedure

4-hydroxy-6-methyl-2-pyrone (2 g, 16 mmol) was stirred in water (25 mL). Allylamine (1.2 ml, 16 mmol) was added to the reaction. The reaction was then heated to 100° C. at which point the reaction became homogeneous. The reaction was stirred at 100° C. for 2 h. The reaction was then allowed to cool to rt after which a white precipitate formed. The precipitate was isolated by suction filtration. After additional washing with water, 1.8 g (69%) of an off-white solid was obtained.

Workup

  1. temperatureto cool to rt after which a white precipitate
  2. customformed
  3. customThe precipitate was isolated by suction filtration
  4. washAfter additional washing with water

Sources & evidence

ORD record
ord-2557de7f97c646f693e9b7a1826f6240
Source dataset
uspto-grants-2006_06
Patent number
US07067540B2

Reaction notes

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