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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832461Generated: November 1, 2026

4-Fluorophenylacetyl chloride → 4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl (4-fluorophenyl)acetate

https://huagongshe.com/reaction/1832461

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorophenylacetyl chlorideHCID 3744988—
ReactantN-(3-[1-(4-hydroxybutyl)-4-piperidinyl]phenyl}-2-methylpropanamideHCID 22048659—
Product4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl (4-fluorophenyl)acetateHCID 22725362—

Reaction Steps

Prepared by Procedure Q1 and Scheme C2 (TEA) using N-{3-[1-(4-hydroxybutyl)-4-piperidinyl]phenyl}-2-methylpropanamide and (4-fluorophenyl)acetyl chloride: ESMS m/e: 455.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-a2170f593a2e45db89f4d9cb329ef41a
Source noteuspto-grants-2006_06