3-Chlorophenol → HCID 58651303, compound

HRID 1832533Notes

Reaction equation

HRID 1832533 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.O[C@H:10]([C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)[CH2:11][N:12]1[CH2:17][CH2:16][CH:15]([C:18]2[CH:19]=[C:20]([NH:24][C:25](=[O:29])[CH:26]([CH3:28])[CH3:27])[CH:21]=[CH:22][CH:23]=2)[CH2:14][CH2:13]1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][CH:7]=1)[O:8][C@@H:10]([C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)[CH2:11][N:12]1[CH2:17][CH2:16][CH:15]([C:18]2[CH:19]=[C:20]([NH:24][C:25](=[O:29])[CH:26]([CH3:28])[CH3:27])[CH:21]=[CH:22][CH:23]=2)[CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 79333-ChlorophenolHCID 69523630HCID 69523630, compound

Product 1

HCID 58651303HCID 58651303, compound

Procedure

Prepared by Procedure B and Scheme B1 using 3-chlorophenol and N-(3-{1-[(2R)-2-hydroxy-2-phenylethyl]-4-piperidinyl}phenyl)-2-methylpropanamide: ESMS m/e: 477.1 (M+H)+.

Workup

  1. customPrepared by Procedure B and Scheme B1

Sources & evidence

ORD record
ord-d0a2f4ba9b0c480cb714ade4ed277a51
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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