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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832664Generated: October 26, 2026

P-Cresol → N-[3-(1-{[6-(2-Fluorophenyl)-1H-indol-3-YL]methyl}-4-piperidinyl)phenyl]-2-methylpropanamide

https://huagongshe.com/reaction/1832664

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-CresolHCID 2879—
Reactant5-BromoindoleHCID 24905—
Reactant2-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 16757255—
Reactant5-(4-methylphenoxy)-1H-indoleHCID 22048835—
Reactant6-(2-fluorophenyl)-1H-indoleHCID 22049000—
ProductN-[3-(1-{[6-(2-Fluorophenyl)-1H-indol-3-YL]methyl}-4-piperidinyl)phenyl]-2-methylpropanamideHCID 22049533—

Reaction Steps

Prepared by Procedure D and Scheme N using 6-(2-fluorophenyl)-1H-indole and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 470.2 (M+H)+. 5-(4-METHYLPHENOXY)-1H-INDOLE: Prepared by Procedure J and Scheme U using 5-bromo-1H-indole and p-cresol: ESMS m/e: 224.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-8a8683c01f6441be89a48b3121cda0e8
Source noteuspto-grants-2006_06