1-benzyl-3-tert-butyl-1H-pyrazole-5-carbonyl chloride → HCID 22049603, compound

HRID 1832792Notes

Reaction equation

HRID 1832792 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][N:8]1[CH2:13][CH2:12][CH:11]([C:14]2[CH:15]=[C:16]([NH:20][C:21](=[O:25])[CH:22]([CH3:24])[CH3:23])[CH:17]=[CH:18][CH:19]=2)[CH2:10][CH2:9]1.[CH2:26]([N:33]1[C:37]([C:38](Cl)=[O:39])=[CH:36][C:35]([C:41]([CH3:44])([CH3:43])[CH3:42])=[N:34]1)[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>C1COCC1>[CH2:26]([N:33]1[C:37]([C:38]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][N:8]2[CH2:13][CH2:12][CH:11]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([NH:20][C:21](=[O:25])[CH:22]([CH3:23])[CH3:24])[CH:15]=3)[CH2:10][CH2:9]2)=[O:39])=[CH:36][C:35]([C:41]([CH3:44])([CH3:43])[CH3:42])=[N:34]1)[C:27]1[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=1

Participants

4

Reactant 2

HCID 27993221-benzyl-3-tert-butyl-1H-pyrazole-5-carbonyl chlorideHCID 16755868N-{3-[1-(6-Aminohexyl)4-piperidinyl]phenyl}-2-methylpropanamide

Product 1

HCID 22049603HCID 22049603, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Prepared by Procedure Q1 (THF) and Scheme AT using N-{3-[1-(6-aminohexyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 1-benzyl-3-tert-butyl-1H-pyrazole-5-carbonyl chloride: ESMS m/e: 586.3 (M+H)+.

Sources & evidence

ORD record
ord-de2f8cb2b0604f8ebab81e4f875f4439
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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