5-(3,5-Dichlorophenoxy)furan-2-carbonyl chloride → HCID 22048678, compound

HRID 1832804Notes

Reaction equation

HRID 1832804 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][CH:8]([C:11]2[CH:12]=[C:13]([NH:17][C:18](=[O:22])[CH:19]([CH3:21])[CH3:20])[CH:14]=[CH:15][CH:16]=2)[CH2:7][CH2:6]1.[Cl:23][C:24]1[CH:25]=[C:26]([CH:36]=[C:37]([Cl:39])[CH:38]=1)[O:27][C:28]1[O:32][C:31]([C:33](Cl)=[O:34])=[CH:30][CH:29]=1>C1COCC1>[Cl:23][C:24]1[CH:25]=[C:26]([CH:36]=[C:37]([Cl:39])[CH:38]=1)[O:27][C:28]1[O:32][C:31]([C:33]([NH:1][CH2:2][CH2:3][CH2:4][N:5]2[CH2:10][CH2:9][CH:8]([C:11]3[CH:16]=[CH:15][CH:14]=[C:13]([NH:17][C:18](=[O:22])[CH:19]([CH3:20])[CH3:21])[CH:12]=3)[CH2:7][CH2:6]2)=[O:34])=[CH:30][CH:29]=1

Participants

4

Reactant 2

HCID 27360285-(3,5-Dichlorophenoxy)furan-2-carbonyl chlorideHCID 16757470N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}2-methylpropanamide

Product 1

HCID 22048678HCID 22048678, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Prepared by Procedure Q1 (THF) and Scheme AT using N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 5-(3,5-dichlorophenoxy)-2-furoyl chloride: ESMS m/e: 558.2 (M+H)+.

Sources & evidence

ORD record
ord-df16437f213c4df7aff63c463e734678
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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