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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832810Generated: October 31, 2026

N-(3-[1-(2-aminoethyl)-4-piperidinyl]phenyl)-2-methylpropanamide → 5-(3,5-Dichlorophenoxy)-N-(2-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}ethyl)-3-furamide

https://huagongshe.com/reaction/1832810

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-[1-(2-aminoethyl)-4-piperidinyl]phenyl)-2-methylpropanamideHCID 16757469—
Reactant5-(3,5-Dichlorophenoxy)-3-furoyl chlorideHCID 22048598—
SolventTetrahydrofuranHCID 8028—
Product5-(3,5-Dichlorophenoxy)-N-(2-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}ethyl)-3-furamideHCID 22049362—

Reaction Steps

Prepared by Procedure Q1 (THF) and Scheme AT using N-{3-[1-(2-aminoethyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 5-(3,5-dichlorophenoxy)-3-furoyl chloride: ESMS m/e: 544.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-468b9c026cb8492193899d3eba44f111
Source noteuspto-grants-2006_06