Potassium Carbonate → HCID 22049154, compound

HRID 1832825Notes

Reaction equation

C([O-])([O-])=O.[K+].[K+].Cl[CH2:8][CH2:9][CH2:10][CH2:11][C:12]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[C:20]([F:23])([F:22])[F:21])=[O:13].[CH3:24][CH:25]([CH3:41])[C:26]([NH:28][C:29]1[CH:34]=[CH:33][CH:32]=[C:31]([CH:35]2[CH2:40][CH2:39][NH:38][CH2:37][CH2:36]2)[CH:30]=1)=[O:27]>>[CH3:24][CH:25]([CH3:41])[C:26]([NH:28][C:29]1[CH:34]=[CH:33][CH:32]=[C:31]([CH:35]2[CH2:40][CH2:39][N:38]([CH2:8][CH2:9][CH2:10][CH2:11][C:12](=[O:13])[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[C:20]([F:23])([F:22])[F:21])[CH2:37][CH2:36]2)[CH:30]=1)=[O:27]

Participants

Reactant 3

HCID 11430Potassium Carbonate

HCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

HCID 220486925-Chloro-1-[2-(trifluoromethyl)phenyl]pentan-1-one

Product 1

HCID 22049154HCID 22049154, compound

Procedure

Prepared by Procedure K and Scheme B1 (K2CO3) using 5-chloro-1-[2-(trifluoromethyl)phenyl]-1-pentanone and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 475.2 (M+H)+.

Sources & evidence

ORD record: ord-b87dfc37a5604120a81d63452c6449ba
Source dataset: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07067534B1

Reaction notes

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