Potassium Carbonate → HCID 22049160, compound

HRID 1832832Notes

Reaction equation

C([O-])([O-])=O.[K+].[K+].[F:7][C:8]([F:23])([F:22])[C:9]1[CH:10]=[C:11]([C:15](=[O:21])[CH2:16][CH2:17][CH2:18][CH2:19]Cl)[CH:12]=[CH:13][CH:14]=1.[CH3:24][CH:25]([CH3:41])[C:26]([NH:28][C:29]1[CH:34]=[CH:33][CH:32]=[C:31]([CH:35]2[CH2:40][CH2:39][NH:38][CH2:37][CH2:36]2)[CH:30]=1)=[O:27]>>[CH3:24][CH:25]([CH3:41])[C:26]([NH:28][C:29]1[CH:34]=[CH:33][CH:32]=[C:31]([CH:35]2[CH2:40][CH2:39][N:38]([CH2:19][CH2:18][CH2:17][CH2:16][C:15](=[O:21])[C:11]3[CH:12]=[CH:13][CH:14]=[C:9]([C:8]([F:23])([F:22])[F:7])[CH:10]=3)[CH2:37][CH2:36]2)[CH:30]=1)=[O:27]

Participants

Reactant 3

HCID 11430Potassium Carbonate

HCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

HCID 220486075-Chloro-1-[3-(trifluoromethyl)phenyl]pentan-1-one

Product 1

HCID 22049160HCID 22049160, compound

Procedure

Prepared by Procedure K and Scheme B1 (K2CO3) using 1-[3-(trifluoromethyl)phenyl]-5-chloro-1-pentanone and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 475.2 (M+H)+.

Sources & evidence

ORD record: ord-0af5d04fd4cb4267b720292f8d5e1571
Source dataset: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07067534B1

Reaction notes

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