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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1833034Generated: October 25, 2026

Sodium Iodide → N-(3-{1-(5-(2-fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamide

https://huagongshe.com/reaction/1833034

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium IodideHCID 5238—
ReactantPotassium CarbonateHCID 11430—
Reactant2-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 16757255—
Reactant5-Chloro-1-(2-fluorophenyl)-1-oxopentaneHCID 22048800—
ProductN-(3-{1-(5-(2-fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamideHCID 22049199—

Reaction Steps

Prepared by Procedure K and Scheme E using K2CO3 instead of Na2CO3 and NaI instead of KI and 5-chloro-1-(2-fluorophenyl)-1-pentanone and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 425.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-4f03461454b84e4b9f0d4375182a03b5
Source noteuspto-grants-2006_06