HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 5-Ethoxy-2-methylpyrazolo[1,5-a]pyrido[3,4-e]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 5-Chloro-2-methylpyrazolo[1,5-a]pyrido[3,4-e]pyrimidine | HCID 21389185 | — |
| Solvent | Water | HCID 962 | — |
| Product | 5-Ethoxy-2-methylpyrazolo[1,5-a]pyrido[3,4-e]pyrimidine | HCID 21389175 | — |
Reaction Steps
2.2 g. of 5-chloro-2-methylpyrazolo[1,5-a]pyrido[3,4-e]pyrimidine are added to a solution of 0.5 g. of sodium in 30 ml. of ethanol. The solution is refluxed with stirring for 12 hours. 10 ml. of water are added and the crystalline 5-ethoxy-2-methylpyrazolo[1,5-a]pyrido[3,4-e]pyrimidine is filtered off, yield: 1.4 g. (61%); m.p. 156.2° (methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04066645 |
| Source dataset | uspto-grants-1978_01 |
| ORD ID | ord-0d9d9bffcc0f401e8a1d1b162124b44d |
| Source note | uspto-grants-1978_01 |