反应详情

2.2 g. of 5-chloro-2-methylpyrazolo[1,5-a]pyrido[3,4-e]pyrimidine are added to a solution of 0.5 g. of sodium in 30 ml. of ethanol. The solution is refluxed with stirring for 12 hours. 10 ml. of water are added and the crystalline 5-ethoxy-2-methylpyrazolo[1,5-a]pyrido[3,4-e]pyrimidine is filtered off, yield: 1.4 g. (61%); m.p. 156.2° (methanol).

1. temperatureThe solution is refluxed
2. filtrationthe crystalline 5-ethoxy-2-methylpyrazolo[1,5-a]pyrido[3,4-e]pyrimidine is filtered off