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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1833409Generated: October 25, 2026

6-Aminopenicillanic acid → Carbenicillin

https://huagongshe.com/reaction/1833409

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Aminopenicillanic acidHCID 11082—
Reactant2,2-Dimethyl-5-phenyl-1,3-dioxane-4,6-dioneHCID 84848—
ProductCarbenicillinHCID 20824—

Reaction Steps

When an equivalent amount of 2.2-tetramethylene-5-phenyl-1.3-dioxane-4.6-dione prepared in the example 3 is substituted for 2.2-dimethyl-5-phenyl-1.3-dioxane-4.6-dione and the reaction with 6-aminopenicillanic acid is carried out as disclosed in the example 1, 6-(α-carboxy-α-phenylacetamido)penicillanic acid (carbenicillin) is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04066664
Source datasetuspto-grants-1978_01
ORD IDord-b18adc18aa7e45aa8288d8e5b0b1dbda
Source noteuspto-grants-1978_01