Hydrochloric Acid → HCID 178514096, compound

HRID 1833532Notes

Reaction equation

HRID 1833532 reaction equation
[Na+].[C:2]([NH:12][CH:13]1[C:36](=[O:37])[N:15]2[C:16]([C:33]([O-:35])=[O:34])=[C:17]([CH:20]([S:27][C:28]3[NH:32][N:31]=[N:30][N:29]=3)[CH2:21][CH2:22][NH:23][C:24]([NH2:26])=[O:25])[CH2:18][S:19][C@H:14]12)(=[O:11])[C@@H:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[OH:4].Cl>>[C:2]([NH:12][CH:13]1[C:36](=[O:37])[N:15]2[C:16]([C:33]([OH:35])=[O:34])=[C:17]([CH:20]([S:27][C:28]3[NH:32][N:31]=[N:30][N:29]=3)[CH2:21][CH2:22][NH:23][C:24]([NH2:26])=[O:25])[CH2:18][S:19][C@H:14]12)(=[O:11])[C@@H:3]([C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1)[OH:4]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178514097HCID 178514097, compound

Product 1

HCID 178514096HCID 178514096, compound

Procedure

An aqueous solution of 7-D-mandelamido-3-[1-(2-ureidoethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acid sodium salt is acidified with 3 N HCl to pH 2.5 and extracted with ethyl acetate. The extract is dried over anhydrous magnesium sulfate and evaporated to dryness to give the title compound.

Workup

  1. extractionextracted with ethyl acetate
  2. dry with materialThe extract is dried over anhydrous magnesium sulfate
  3. customevaporated to dryness

Sources & evidence

ORD record
ord-363cf8db52544609be278677adb61338
Source dataset
uspto-grants-1978_01
Patent number
US04066761

Reaction notes

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