2-Imidazolidinone → HCID 13031745, compound

HRID 1833592Notes

Reaction equation

HRID 1833592 reaction equation
[CH2:1]1[NH:6][C:4](=[O:5])[NH:3][CH2:2]1.[N:7]1([S:13](Cl)(=[O:15])=[O:14])[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1>CO.C(O)(C)C>[N:7]1([S:13]([N:3]2[CH2:2][CH2:1][NH:6][C:4]2=[O:5])(=[O:15])=[O:14])[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1

Participants

4

Reactant 2

HCID 84532-ImidazolidinoneHCID 11298344Piperidine-1-sulfonyl chloride

Product 1

HCID 13031745HCID 13031745, compound

Reagents, catalysts & solvents 1

HCID 21255859Isopropanol methanolSolvent

Procedure

To 17.4 of ethyleneurea is added with shaking 36 g of piperidinosulfonyl chloride (b.p. 130°/11 mm) and the mixture kept under nitrogen at 100° for 3 hrs. The mixture is cooled and the gummy material treated with methanol-isopropanol (1:1) to give a granular product of 1-piperidinosulfonyl-2-oxo-tetrahydroimidazole which melts at 201° on recrystallization from methanol.

Workup

  1. temperatureThe mixture is cooled

Sources & evidence

ORD record
ord-8de22fefe4534509857675bddb4a0709
Source dataset
uspto-grants-1978_01
Patent number
US04066778

Reaction notes

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