Phosphorus oxychloride → 2-(4-Pentylphenyl)pyrimidine-5-carbonitrile

Participants

Reaction Steps

9.1 G. of 2-(p-n-pentylphenyl)-5-pyrimidinecarboxamide are reacted with 100 ml. of phosphorus oxychloride with the exclusion of moisture, worked up and purified in a manner analogous to that described in Example 7. The pure, colorless 5-cyano-2-(4-n-pentylphenyl)-pyrimidine has a melting point of 96.0°-96.2° C. and a clearing point of 109.0° C.

Provenance & Evidence