2-Chloroethyl isocyanate → HCID 54327014, compound

Participants

Reaction Conditions

Reaction Steps

41 g of β-chloroethyl isocyanate were added to a solution of 28.7 g of 3-hydroxy-5-ethoxy-1,2,4-thiadiazole in 500 ml of benzene and after stirring for 17 hours at 20° C, the mixture was filtered. The filtrate was evaporated to dryness and the residue was empasted with isopropyl ether and was dried to obtain 47 g of 2-(N-β-chloroethylcarbamoyl)-5-ethoxy-1,2,4-thiadiazole-3-one melting at 82° C.

Provenance & Evidence