Triphenyl phosphite → HCID 12221446, compound

HRID 1833986Notes

Reaction equation

HRID 1833986 reaction equation
[CH:1]1(O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([CH3:15])[CH:10]=1.P(OC1C=CC=CC=1)(OC1C=CC=CC=1)OC1C=CC=CC=1>O>[CH:1]1([NH:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([CH3:15])[CH:10]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 7540Triphenyl phosphiteHCID 7934m-ToluidineHCID 7966Cyclohexanol

Product 1

HCID 12221446HCID 12221446, compoundYield 60%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

200 parts of cyclohexanol, 214 parts of m-toluidine and 10 parts of triphenyl phosphite are heated for 20 hours at 230° C in a stirred autoclave. The autoclave is then let down and the water of reaction formed, unconverted toluidine and excess alcohol are distilled off. 227 parts of N-cyclohexyl-m-toluidine, corresponding to a yield of 60% of theory, distil at a boiling point of 165° - 170° C/15 mm Hg.

Workup

  1. customformed
  2. distillationunconverted toluidine and excess alcohol are distilled off
  3. custom227 parts of N-cyclohexyl-m-toluidine, corresponding to a yield of 60% of theory, distil at a boiling point of 165° - 170° C/15 mm Hg

Sources & evidence

ORD record
ord-a242bdeb9d274cbc9266b6b2482779a4
Source dataset
uspto-grants-1978_01
Patent number
US04067903

Reaction notes

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