7-Aminocephalosporanic acid → HCID 178514072, compound

HRID 1833999Notes

Reaction equation

HRID 1833999 reaction equation
CC(O[CH2:5][C:6]1[CH2:15][S:14][C@@H:9]2[C@H:10]([NH2:13])[C:11](=[O:12])[N:8]2[C:7]=1[C:16]([OH:18])=[O:17])=O.[SH:19][C:20]1[N:21]=[N:22][NH:23][CH:24]=1.C(OC([NH:32][CH:33]([C:37]1[CH:42]=[CH:41][CH:40]=[C:39]([NH:43][C:44]([NH2:46])=[O:45])[CH:38]=1)[C:34](O)=[O:35])=O)(C)(C)C>>[NH:23]1[CH:24]=[C:20]([S:19][CH2:5][C:6]2[CH2:15][S:14][C@@H:9]3[CH:10]([NH:13][C:34](=[O:35])[CH:33]([C:37]4[CH:42]=[CH:41][CH:40]=[C:39]([NH:43][C:44]([NH2:46])=[O:45])[CH:38]=4)[NH2:32])[C:11](=[O:12])[N:8]3[C:7]=2[C:16]([OH:18])=[O:17])[N:21]=[N:22]1

Participants

4

Reactant 3

HCID 4413287-Aminocephalosporanic acidHCID 20327929HCID 20327929, compoundHCID 178527738HCID 178527738, compound

Product 1

HCID 178514072HCID 178514072, compound

Procedure

When 7-ACA, 4-mercapto-1,2,3-triazole, and α-t-butoxycarbonylamino-m-ureidophenylacetic acid are reacted according to the procedure of Example 5 the title compound is obtained.

Sources & evidence

ORD record
ord-c22bb9f543c24f049872212a0d0950eb
Source dataset
uspto-grants-1978_01
Patent number
US04067976

Reaction notes

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