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HRID1834174

反应详情

EQUATION

反应方程式

HRID 1834174 的结构方程式

REACTANTS

反应物

2
结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：COC(=O)c1cc(C(=O)N(C)C(CO)(CO)CO)cc([N+](=O)[O-])c1
HCID22749370

未命名化合物

PRODUCTS

生成物

1
结构：CN(C(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1)C(CO)(CO)CO
HCID22749369

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Methyl N-methyl-5-nitro-N-[tris(hydroxymethyl)methyl]isophthalamate is stirred with one equivalent of sodium hydroxide in aqueous methanol. The reaction mixture is concentrated to remove the methanol, diluted with water and acidified with mineral acid to provide crystalline N-methyl-5-nitro-N-[tris (hydroxymethyl)methyl]isophthalamic acid.

WORKUP

后处理

  1. concentrationThe reaction mixture is concentrated
  2. customto remove the methanol
  3. additiondiluted with water