Paraldehyde → Ethyl 3-ethyl-4,5-dimethyl-1H-pyrrole-2-carboxylate

HRID 1834427Notes

Reaction equation

HRID 1834427 reaction equation
[CH3:1][C:2]1[NH:3][C:4]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:5][C:6]=1[CH3:7].[CH3:13][CH:14]1OC(C)OC(C)O1>>[CH3:1][C:2]1[NH:3][C:4]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[C:5]([CH2:13][CH3:14])[C:6]=1[CH3:7]

Participants

3

Reactant 2

HCID 31264ParaldehydeHCID 137478Ethyl 4,5-dimethyl-1H-pyrrole-2-carboxylate

Product 1

HCID 606892Ethyl 3-ethyl-4,5-dimethyl-1H-pyrrole-2-carboxylate

Procedure

As in Example 32 but using 2,3-dimethyl-5-carbethoxy-pyrrole and paraldehyde. Colourless prisms (51%), m.p. 95°-97° (lit16) m.p. 97°). Anal. Calc. for C11H17NO2 : C, 67.66; H, 8.78; N, 7.17. Found: C, 67.59; H, 8.49; N, 7.23.

Sources & evidence

ORD record
ord-b4c6756eab464ad8938fe132f2793e02
Source dataset
uspto-grants-1978_01
Patent number
US04070366

Reaction notes

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