Paraldehyde → Ethyl 4-ethyl-2,5-dimethyl-1H-pyrrole-3-carboxylate

HRID 1834430Notes

Reaction equation

HRID 1834430 reaction equation
[CH3:1][C:2]1[NH:3][C:4]([CH3:12])=[CH:5][C:6]=1[C:7]([O:9][CH2:10][CH3:11])=[O:8].[CH3:13][CH:14]1OC(C)OC(C)O1>>[CH3:12][C:4]1[NH:3][C:2]([CH3:1])=[C:6]([C:7]([O:9][CH2:10][CH3:11])=[O:8])[C:5]=1[CH2:13][CH3:14]

Participants

3

Reactant 2

HCID 31264ParaldehydeHCID 1374822,5-Dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester

Product 1

HCID 20373173Ethyl 4-ethyl-2,5-dimethyl-1H-pyrrole-3-carboxylate

Procedure

As in Example 32 but using 2,5-dimethyl-3-carbethoxy-pyrrole and paraldehyde. Colourless crystals (75%), m.p. 105°-107° (lit18) 106°-107°). Anal. Calc. for C11H17NO2 : C, 67.66; H, 8.78; N, 7.17. Found: C, 67.54; H, 8.69; N, 7.28.

Sources & evidence

ORD record
ord-07122a63e55a4ef091681ce6c9f611f7
Source dataset
uspto-grants-1978_01
Patent number
US04070366

Reaction notes

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