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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1834449Generated: October 29, 2026

Formaldehyde → 2,3,4,5-Tetramethylpyrrole

https://huagongshe.com/reaction/1834449

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantEthyl 2,4,5-trimethyl-1H-pyrrole-3-carboxylateHCID 137484—
Product2,3,4,5-TetramethylpyrroleHCID 70484—

Reaction Steps

2,4,5-Trimethyl-3-carbethoxy-pyrrole was reductively alkylated using paraformaldehyde to yield tetramethyl pyrrole. ##STR82##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04070366
Source datasetuspto-grants-1978_01
ORD IDord-6365e83bee504479b79de9b240ffc487
Source noteuspto-grants-1978_01