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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1834452Generated: November 2, 2026

Formaldehyde → 1H-Pyrrole, 3-ethyl-2,4,5-trimethyl-

https://huagongshe.com/reaction/1834452

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
Reactant3,5-Dimethyl-4-ethyl-1H-pyrrole-2-carboxylic acid ethyl esterHCID 137480—
Product1H-Pyrrole, 3-ethyl-2,4,5-trimethyl-HCID 10628—

Reaction Steps

2,4-Dimethyl-3-ethyl-5-carbethoxy-pyrrole was reductively alkylated with paraformaldehyde to yield 3-ethyl-2,4,5-trimethyl-pyrrole. ##STR85##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04070366
Source datasetuspto-grants-1978_01
ORD IDord-c36a4c5ad81e42129095df4a35e5a1ee
Source noteuspto-grants-1978_01