Formaldehyde → 2,4-Dimethyl-3,5-di(n-propyl)-pyrrole

HRID 1834463Notes

Reaction equation

[C:1]([C:6]1[NH:7][C:8]([CH2:15][CH2:16][CH3:17])=[C:9]([CH3:14])[C:10]=1[CH2:11][CH2:12][CH3:13])(OCC)=O.C=O>>[CH3:1][C:6]1[NH:7][C:8]([CH2:15][CH2:16][CH3:17])=[C:9]([CH3:14])[C:10]=1[CH2:11][CH2:12][CH3:13]

Participants

Reactant 2

HCID 712Formaldehyde

HCID 203731362,4-Di-n-propyl-3-methyl-5-carbethoxypyrrole

Product 1

HCID 203731832,4-Dimethyl-3,5-di(n-propyl)-pyrrole

Procedure

2-Carbethoxy-3,5-di(n-propyl)-4-methyl-pyrrole was reductively alkylated with paraformaldehyde to yield 2,4-dimethyl-3,5-di(n-propyl)-pyrrole. ##STR104##

Sources & evidence

ORD record: ord-1e1380677e6742ba98db1222dfd98178
Source dataset: uspto-grants-1978_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04070366

Reaction notes

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