3-Aminobenzoic Acid → HCID 20038187, compound

HRID 1834540Notes

Reaction equation

HRID 1834540 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]=[CH:12][C:13]=1[O:14]C(=O)C)[CH2:6][CH2:7][C:8](Cl)=[O:9].[NH2:18][C:19]1[CH:20]=[C:21]([CH:25]=[CH:26][CH:27]=1)[C:22]([OH:24])=[O:23]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]=[CH:12][C:13]=1[OH:14])[CH2:6][CH2:7][C:8]([NH:18][C:19]1[CH:20]=[C:21]([CH:25]=[CH:26][CH:27]=1)[C:22]([OH:24])=[O:23])=[O:9]

Participants

3

Reactant 2

HCID 74193-Aminobenzoic AcidHCID 14269669HCID 14269669, compound

Product 1

HCID 20038187HCID 20038187, compound

Procedure

In a similar manner except that 3-methoxy-4-acetoxyhydrocinnamoyl chloride was used in place of the 4-acetoxycinnamoyl chloride used in Example 1 for reaction with 3-aminobenzoic acid and the reaction product was hydrolyzed, 3-(3'-methoxy-4'-hydroxyhydrocinnamoylamino)benzoic acid was obtained. After recrystallization from an aqueous alcohol, this product had a melting point of 218°-220° C.

Sources & evidence

ORD record
ord-354dff33cfb54574ae9c8b59491254ca
Source dataset
uspto-grants-1978_01
Patent number
US04070484

Reaction notes

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