2,4,5-Trichloroaniline → (Methylsulfonyl)(2,4,5-trichlorophenyl)amine

HRID 1834726Notes

Reaction equation

HRID 1834726 reaction equation
[Cl:1][C:2]1[CH:8]=[C:7]([Cl:9])[C:6]([Cl:10])=[CH:5][C:3]=1[NH2:4].[CH3:11][S:12](Cl)(=[O:14])=[O:13]>C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[CH:8]=[C:7]([Cl:9])[C:6]([Cl:10])=[CH:5][C:3]=1[NH:4][S:12]([CH3:11])(=[O:14])=[O:13]

Participants

4

Reactant 2

HCID 124872,4,5-TrichloroanilineHCID 31297Methanesulfonyl chloride

Product 1

HCID 2427123(Methylsulfonyl)(2,4,5-trichlorophenyl)amine

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

A mixture of 2,4,5-trichloroaniline (39.3 g.), methane sulfonyl chloride (22.9 g. ) and 100 ml. of xylene were heated together under reflux conditions for 18 hours. The mixture was then allowed to cool, which formed a brown precipitate. The product was worked up in the same manner as set forth in Example 1 to yield 24.0 g. of product, m.p. 144°-145° C.

Workup

  1. temperatureto cool
  2. customwhich formed a brown precipitate
  3. customto yield 24.0 g

Sources & evidence

ORD record
ord-36fa2833a8e7433d96d0e4d813b36b5b
Source dataset
uspto-grants-1978_01
Patent number
US04071352

Reaction notes

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