Benzene → HCID 20324732, compound

HRID 1834749Notes

Reaction equation

HRID 1834749 reaction equation
C1C=CC=CC=1.[CH2:7]([CH:9]1[NH:13][CH2:12][CH:11]([CH3:14])[O:10]1)[CH3:8].[CH3:15][S:16](Cl)(=[O:18])=[O:17]>C(N(CC)CC)C>[CH2:7]([CH:9]1[N:13]([S:16]([CH3:15])(=[O:18])=[O:17])[CH2:12][CH:11]([CH3:14])[O:10]1)[CH3:8]

Participants

5

Reactant 3

HCID 241Benzene2×HCID 31297Methanesulfonyl chlorideHCID 20371823HCID 20371823, compound

Product 1

HCID 20324732HCID 20324732, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

A solution was formed containing 25 ml. of benzene and 6 g. of 2-ethyl-5-methyl oxazolidine suspended in 24 ml. of benzene. Then, 5.5 g. of triethylamine was added. The solution was cooled in an ice bath, wherein 5.8 g. of methane sulfonyl chloride was added dropwise with stirring to yield 6.4 g. of product, nD30 = 1.4778.

Workup

  1. customA solution was formed
  2. additioncontaining 25 ml
  3. temperatureThe solution was cooled in an ice bath, wherein 5.8 g
  4. customto yield 6.4 g

Sources & evidence

ORD record
ord-0665bf75aaaa4ec6a6b22a5fed931942
Source dataset
uspto-grants-1978_01
Patent number
US04071353

Reaction notes

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