Sodium Hydroxide → HCID 19819855, compound

Participants

Reaction Conditions

Reaction Steps

255 g of p-butylsulphonylacetanilide, in a mixture of 1.5 l of water and 300 ml of concentrated hydrochloric acid, are boiled for 1 hour under reflux. After cooling to 0° C, the product is diazotised with a solution of 70 g of NaNO2 in 175 ml of water. The filtered diazonium salt solution is added, at 5°-10° C, to a mixture of 750 g of 40% strength sodium sulphite solution and 750 ml of water which had been adjusted to pH 7 with concentrated sodium hydroxide solution, the pH being maintained at 6-7 by means of concentrated sodium hydroxide solution. After standing overnight, 300 ml of concentrated hydrochloric acid are added and the mixture is boiled for 1 hour. p-Butylsulphonylphenylhydrazine of melting point 138° C (from ethanol) is obtained, in a yield of approx. 70- 75% of theory, from the cooled solution by careful addition of alkali.

Provenance & Evidence