Methyl Isocyanate → HCID 53729079, compound

HRID 1834885Notes

Reaction equation

HRID 1834885 reaction equation
[N:1](=[C:3]1[CH:8]([CH3:9])[N:7]([CH2:10][CH2:11][CH2:12][CH3:13])[C:6](=[O:14])[CH2:5][S:4]1)[OH:2].[CH3:15][N:16]=[C:17]=[O:18]>C(N(CC)CC)C>[CH3:15][NH:16][C:17]([O:2][N:1]=[C:3]1[CH:8]([CH3:9])[N:7]([CH2:10][CH2:11][CH2:12][CH3:13])[C:6](=[O:14])[CH2:5][S:4]1)=[O:18]

Participants

4

Reactant 2

HCID 12228Methyl IsocyanateHCID 85945284HCID 85945284, compound

Product 1

HCID 53729079HCID 53729079, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Utilizing the procedure of Example V, 2-oximino-3-methyl-4-butyltetrahydro-1,4-thiazin-5-one was reacted with methyl isocyanate in the presence of triethylamine to yield 7.0 of 2-[O-(methylcarbamoyl)oximino]-3-methyl-4-butyltetrahydro-1,4-thiazin-5-one, m.p. 118°-120° C. An nmr spectrum supported the proposed structure.

Sources & evidence

ORD record
ord-662d93603b7e4514a8657a878ac85cb8
Source dataset
uspto-grants-1978_01
Patent number
US04071627

Reaction notes

Loading…