1beta-Methyl-5-androstene-3beta,17beta,19-triol 3,17-diacetate → 1beta-Methyl-5alpha-androstane-3beta,17beta,19-triol 3,17-diacetate

関与物質

反応手順

A solution of 1β-methyl-5-androstene-3β,17β,19-triol 3,17-diacetate in methanol is hydrogenated with a 10% palladium-on-carbon catalyst at atmospheric pressure for about 8 hours. The catalyst is removed by filtration, the filtrate is concentrated to a small volume, cooled and filtered. The residue is crystallized from a solution of hexane to yield 1β-methyl-5α-androstane-3β,17β,19-triol 3,17-diacetate.

情報源と証拠