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HRID1834982

反应详情

EQUATION

反应方程式

HRID 1834982 的结构方程式

REACTANTS

反应物

1
结构：CC(=O)O[C@@H]1CC2=CC[C@H]3[C@@H]4CC[C@H](OC(C)=O)[C@@]4(C)CC[C@@H]3[C@@]2(CO)[C@H](C)C1
HCID70614873

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)O[C@@H]1C[C@@H]2CC[C@H]3[C@@H]4CC[C@H](OC(C)=O)[C@@]4(C)CC[C@@H]3[C@@]2(CO)[C@H](C)C1
HCID70614636

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

A solution of 1β-methyl-5-androstene-3β,17β,19-triol 3,17-diacetate in methanol is hydrogenated with a 10% palladium-on-carbon catalyst at atmospheric pressure for about 8 hours. The catalyst is removed by filtration, the filtrate is concentrated to a small volume, cooled and filtered. The residue is crystallized from a solution of hexane to yield 1β-methyl-5α-androstane-3β,17β,19-triol 3,17-diacetate.

WORKUP

后处理

  1. customThe catalyst is removed by filtration
  2. concentrationthe filtrate is concentrated to a small volume
  3. temperaturecooled
  4. filtrationfiltered
  5. customThe residue is crystallized from a solution of hexane