反应详情

A solution of 2-hydroxy-5-(methylsulfonyl)benzoic acid (5.80 g, 26.8 mmol, prepared using procedure in J. Chem. Soc., Perkin Trans 1 1978, 6, 633-638) in MeOH (150 ml) at 0° C. was saturated with HCl (g). The solution was warmed to r.t. and heated to reflux for 3 h. The solid which formed upon cooling was filtered and dried to afford the title compound (4.40 g, 19.1 mmol, 71%).

1. customat 0° C.
2. temperatureheated
3. temperatureto reflux for 3 h
4. customThe solid which formed
5. temperatureupon cooling
6. filtrationwas filtered
7. customdried