反应详情

Methyl 4-(3-methyl-1-oxobutyl)-1H-pyrrole-3-carboxylate (Example 1, step b, 7.8 g) and methylhydrazine (6 ml) were heated at reflux for 18 hours. The solvent was evaporated and the residue was chromatographed, eluting with dichloromethane-ethanol (19:1), to give the sub-title compound as a sand coloured solid (5.2 g).

1. temperatureat reflux for 18 hours
2. customThe solvent was evaporated
3. customthe residue was chromatographed
4. washeluting with dichloromethane-ethanol (19:1)