(2-Methyl-4,5-(methylenedioxy)phenyl)(2-chloro-4-trifluoromethyl-3-pyridyl)methanol → 3-[4,5-(Methylenedioxy)-2-methylbenzoyl]-2-chloro-4-trifluoromethylpyridine

Participants

Reaction Steps

Using 1.5 g (4.3 mmol) of (2-methyl-4,5-(methylenedioxy)phenyl)(2-chloro-4-trifluoromethyl-3-pyridyl)methanol obtained in step (c) and 8.0 g (92 mmol) of manganese dioxide, 0.3 g (yield 22%) of 3-[4,5-(methylenedioxy)-2-methylbenzoyl]-2-chloro-4-trifluoromethylpyridine (compound No. 13; m.p. 119-122° C.) was obtained by a process in accordance with step (b) of Synthesis Example 1.

Provenance & Evidence