HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 67255836, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 6-Chloroimidazo(2,1-b)(1,3)thiazole-5-sulfonyl chloride | HCID 2799717 | — |
| Reactant | 3,5-Dichloro-4-(napthalen-2-ylsulfanyl)-phenylamine | HCID 22148834 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67255836 | HCID 67255836 | 67.7% |
Reaction Steps
The title compound was prepared using the method of example 94, starting with 3,5-dichloro-4-(naphthalen-2-ylsulfanyl)-phenylamine (90) (150 mg, 0.47 mmol), pyridine (Aldrich, 0.19 mL, 2.34 mmol) and 6-chloro-imidazo[2,1-b]thiazole-5-sulfonyl chloride (Maybridge, 132 mg, 0.52 mmol) in THF. 172 mg (65%) of 102 was obtained as a pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06770648B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-b7216f5d6a6749899ef08d656546ea67 |
| Source note | uspto-grants-2004_08 |