Ethyl xanthate → HCID 178509540, compound

HRID 1835524Notes

Reaction equation

HRID 1835524 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1Cl)[C:5]#[N:6].C(O[C:14]([SH:16])=[S:15])C.[K]>CN(C=O)C>[SH:16][C:14]1[S:15][C:9]2[CH:8]=[CH:7][C:4]([C:5]#[N:6])=[CH:3][C:2]=2[N:1]=1

Participants

5

Reactant 3

HCID 8823Ethyl xanthateHCID 1044643-Amino-4-chlorobenzonitrileHCID 5462222Potassium

Product 1

HCID 178509540HCID 178509540, compoundYield 49%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The title compound was prepared using the method of example 239, starting with 3-amino-4-chloro-benzonitrile (242) (9.0 g, 59.0 mmol), O-ethylxanthic acid, potassium salt (Lancaster, 21.23 g, 132.7 mmol) in DMF (90 mL). 5.6 g (49%) of compound 243 was obtained as a pale brown solid.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-6e85a5ad94a841eabe5565f06d14af72
Source dataset
uspto-grants-2004_08
Patent number
US06770648B2

Reaction notes

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