HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorotrityl chloride → Diisopropylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorotrityl chloride | HCID 94524 | — |
| Reactant | Fmoc-Cha-OH | HCID 978326 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Diisopropylamine | HCID 7912 | — |
| Product | Fmoc-Cha-OH | HCID 978326 | — |
Reaction Steps
Fmoc Cha-OH (1 mmol each time) was double coupled to the chlorotrityl chloride resin in the standard way using, dichloromethane (5 ml each time) with diisopropylamine (2 eq, 348 μl each time) to give Fmoc-Cha-resin.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06770627B1 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-b1895a8f4cd14b53a3a943308ffa8083 |
| Source note | uspto-grants-2004_08 |