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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1835581Generated: October 25, 2026

(3-Chlorophenyl)boronic acid → Ethyl 2-{4-[3-(3-chlorophenyl)phenoxy]phenyl}-1-cyclohexylbenzimidazole-5-carboxylate

https://huagongshe.com/reaction/1835581

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Chlorophenyl)boronic acidHCID 2734323—
ReactantEthyl 2-[4-(3-bromophenoxy)phenyl]-1-cyclohexylbenzimidazole-5-carboxylateHCID 9914616—
ProductEthyl 2-{4-[3-(3-chlorophenyl)phenoxy]phenyl}-1-cyclohexylbenzimidazole-5-carboxylateHCID 1023101985.6%

Reaction Steps

Ethyl 2-[4-(3-bromophenoxy)phenyl]-1-cyclohexylbenzimidazole-5-carboxylate (65 g) obtained in Example 1 and 3-chlorophenylboronic acid (23 g) were treated in the same manner as in Example 5 to give the title compound (59 g, yield 85%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06770666B2
Source datasetuspto-grants-2004_08
ORD IDord-aaf9765864a54fc4992ee6b11ecf0c70
Source noteuspto-grants-2004_08